Igf3: a novel player in fish reproduction

Abstract As in other vertebrates, fish reproduction is tightly controlled by gonadotropin signaling. One of the most perplexing aspects action on germ cell biology restricted expression receptors somatic cells gonads. Therefore, identification factors conveying gonadotropins particularly important for understanding mechanism reproduction. Insulin-like growth (Igfs) are recognized as key regulating triggering a series physiological processes vertebrates. Recently, novel member Igfs called Igf3 has been identified teleost. Different from conventional Igf1 and Igf2 that ubiquitously expressed majority tissues, solely or highly The role mediating through Igf type 1 receptor several oogenesis spermatogenesis have demonstrated species. In this review, we will summarize existing data Igf3. This new information obtained provides insight into elucidating molecular reproduction, also highlights importance system signaling animal